Sydney Mass Spectrometry

"-omics" specialists for the life sciences

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Who we are

Sydney Mass Spectrometry provides access to cutting-edge instrumentation and expert assistance for proteomics, glycomics, metabolomics, lipidomics, and mass spectrometry imaging.

Our facilities feature a diverse portfolio of 20 mass spectrometers, with extensive data processing and analysis packages, and are located across three sites: the Charles Perkins Centre at the University of Sydney Camperdown Campus, the Kolling Institute at Royal North Shore Hospital and the Biomedical Building in the South Eveleigh precinct. 

Our specialist technical staff have over 125 years’ combined experience and are on hand to provide high-level training, project development, and contract research services.

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New researchers can come and run their own samples via the ‘Research Hotel’, just follow this 3-step process.

  1. Consultation. After receiving your enquiry, our staff will put together a viable project design, taking into account factors such as experimental scope, instrument requirements, and budget.
  2. Registration. Researchers from outside the University will first need to request an account on the Facility Management System and all researcher (internal and external) need to lodge an project request.
  3. Training. We will organise bespoke training programs specific to each new researcher’s needs.  Once completed they will have autonomous access to the facilities.

We welcome enquiries regarding our range of research services available on a contractual basis. Examples of our services include:

  • Protein identification – either by peptide mass fingerprinting (for samples like bands on a gel) or by one dimensional liquid chromatography coupled to tandem mass spectrometry (1D LC-MS) which can be used for more complex protein mixtures, such as pull-down assays
  • Quantitative discovery proteomics – for a comprehensive analysis of complex protein mixtures which typically identifies and quantifies thousands of proteins. There is a choice of label-based or label-free methods
  • Targeted metabolomics – there is a growing repertoire of targeted assays covering groups of compounds such as bile acids, central carbon metabolites, short chain fatty acids or synthetic compounds such as PFAS
  • Targeted lipidomics – our method covers >550 lipid species, across 34 lipid classes and subclasses
  • Service research – for the more challenging research, where we don’t have an established assay, we can design a bespoke method to meet your research goals.

Recognition of the contribution that core facility staff make to research is vital to the continuation of those facilities and the career progression of individuals.  Facility staff are highly skilled scientists who contribute technically and intellectually to research projects.  It is therefore important to acknowledge them properly in publications and presentations.

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Contact us

Locations

Sydney Mass Spectrometry has locations across multiple sites including:

  • Charles Perkins Centre (Administration office)
  • Kolling Institute, Royal North Shore Hospital.
  • Biomedical Building, South Eveleigh precinct

Delivery address

Sydney Mass Spectrometry
via The Hub Loading Dock
Charles Perkins Centre (D17)
Orphans School Creek Lane
Camperdown
University of Sydney, NSW, 2006
Dock receiving time: 08:00 – 16:00, Mon - Fri.