Our research
Leaders in infectious diseases research
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We are global leaders in emerging infections and antimicrobial resistance (AMR). These are existential threats for humanity and require solutions that address the interdependent roles of humans, animals, the environment and socio-political contexts.
They require fundamental research into pathogen biology, genomics and host pathogen interactions to develop tools to advance new public health and therapeutic solutions – and ethical and social research to ensure successful implementation into practice and policy.
We take a multidisciplinary approach, linking pathogens, hosts and the environment in a one planet, one health framework. Our special interest groups extend from medical science and public health to the arts, ethics and social sciences.
We are tackling the challenges of emerging and re-emerging infectious diseases.
$1.49 million | 2023 - 2027
Led by Sydney ID’s Professor Ramon Shaban, HIRAID Aged Care improves the health and wellbeing of older individuals living in residential aged care.
Anchored in a strong foundation of research evidence and expert input, HIRAID® improves the clinical outcomes, quality of patient assessment, recognition & response to clinical deterioration, nurses’ communication, decision-making, situational awareness & task management skills, and nurses' self-efficacy and levels of anxiety.
HIRAID® Aged Care will meet the contemporary practice needs of RNs working in aged care having been co-designed and tested by them and the recipients of their care in partnership with leading aged care providers and other agencies committed to the provision of quality care in aged care nationally.
Funding body: Medical Research Future Fund - Department of Health and Aged Care
$19 million | 2022 - 2027
Led by Sydney ID’s Deputy Director, Professor Jamie Triccas, the Advancing Vaccine Adjuvant Research for tuberculosis (AVAR-T) project aims to reduce the global burden of tuberculosis (TB).
The University of Sydney and The Centenary Institute, together with collaborators have been awarded an AU$19 million contract from the National Institute of Allergy and Infectious Diseases, part of the US National Institutes of Health (NIH), to develop the next generation of tuberculosis (TB) vaccines.
TB, a disease that primarily affects the lungs, is caused by infection from the bacteria Mycobacterium tuberculosis. Approximately 1.5 million people die from TB each year and it is a leading cause of death globally.
Investigator: Professor Jamie Triccas
Funding body: US National Institutes of Health (NIH)
$18.2 million | 2022 - 2027
Sydney ID’s Deputy Director, Professor Jamie Triccas, leads an international consortium awarded up to US$19.3 million by The Coalition for Epidemic Preparedness Innovations to support the development of a 'variant-proof' SARS-CoV-2 vaccine candidate.
The multidisciplinary collaboration of Bharat Biotech International Ltd (Bharat Biotech), India, ExcellGene SA, Switzerland and the University of Sydney, Australia seeks to establish preclinical and clinical proof of concept for a protein subunit vaccine designed to provide broad protection against all known SARS-CoV-2 variants of concern, as well as future and yet to emerge variants of the virus.
Investigator: Professor Jamie Triccas
Funding body: Coalition for Epidemic Preparedness Innovations (CEPI)
$4.3 million
Staph aureus (golden staph) bloodstream infections are common and deadly, despite antibiotics. Phages are viruses that infect and kill bacteria. We have been treating patients with severe infections using phages produced by our team since 2022.
This trial, led by Sydney ID’s Dr Ameneh Khatami, will investigate use of a locally produced 2-phage combination (cocktail) that targets the golden staph bacteria to see if it provides an advantage in addition to antibiotics in treating patients with severe golden staph bloodstream infections.
Investigator: Dr Ameneh Khatami
Funding body: National Health and Medical Research Council (NHMRC) Clinical Trials and Cohort Studies scheme
$485,000 | 2024 - 2026
Sydney ID EMCR, Dr Kenya Fernandes has been awarded a prestigious Australian Research Council Discovery Early Career Researcher Award to lead pioneering research into the intricate relationships between bees and fungi within Australian ecosystems.
Dr Fernandes will explore how specific fungi interact with both honey bee and native bee populations, exploring their nutritional and functional roles. She will investigate how bees use antimicrobial hive products, such as honey and plant resins, to naturally regulate fungal growth – potentially identifying leads for the development of new eco-friendly fungicides based on these natural compounds.
Investigator: Dr Kenya Fernandes
Funding body: Australian Research Council Discovery Early Career Researcher Award (DECRA)
We conduct world-leading research that transforms infectious diseases prevention, management and control. Explore a selection of our published research.
| Title | Publication | Author |
|---|---|---|
| Antimicrobial susceptibility profiles of invasive bacterial infections among children from low- and middle-income countries in the Western Pacific Region (WPRO) – a systematic review and meta-analysis | The Lancet Regional Health - Western Pacific | Nerida Moorea, Elizabeth A. Ashley, Benjamin F.R. Dickson, Anousone Douangnouvong, Pathana Panyaviset, Paul Turner, Phoebe C.M. Williams |
| Beyond bacteria: the growing threat of antifungal resistance | The Lancet | Norman van Rhijn, Sevtap Arikan-Akdagli, Justin Beardsley, Felix Bongomin, Arunaloke Chakrabarti, Sharon C-A Chen, Tom Chiller, Arnaldo Lopes Colombo, Nelesh P Govender, Ana Alastruey-Izquierdo, Sarah E Kidd, Michaela Lackner, Ruoyu Li, Ferry Hagen |
| Closing the policy–practice gap for tuberculosis preventive treatment | The Lancet Child and Adolescent Health | Martina Casenghi, Jennifer Furin, Moorine P Sekadde, Sangeeta Sharma, Ben J Marais |
| Coverage gaps in empiric antibiotic regimens used to treat serious bacterial infections in neonates and children in Southeast Asia and the Pacific | The Lancet Regional Health - Southeast Asia | Phoebe C.M. Williams, Mark Jones, Thomas Snelling, Robert Duguid, Nerida Moore, Benjamin Dickson, Yue Wu, Jessica Saunders, Priyali Wijeratne, Anousone Douangnouvong, Elizabeth A. Ashley, Paul Turner |
| Demographics of sources of HIV-1 transmission in Zambia: a molecular epidemiology analysis in the HPTN 071 PopART study | The Lancet Microbe | Matthew Hall, Tanya Golubchik, David Bonsall, Lucie Abeler-Dörner, Mohammed Limbada, Barry Kosloff, Ab Schaap, Mariateresa de Cesare, George MacIntyre-Cockett, Newton Otecko, William Probert, Oliver Ratmann, Ana Bulas Cruz, Estelle Piwowar-Manning, David N Burns, Myron S Cohen, Deborah J Donnell, Susan H Eshleman, Musonda Simwinga, Sarah Fidler, Richard Hayes, Helen Ayles, Christophe Fraser, Yaw Agyei, Nulda Beyers, Peter Bock, Virginia Bond, Justin Bwalya, Anne Cori, Anneen Deventer, Rory Dunbar, Wafaa El-Sadr, Lynda Emel, Sian Floyd, Sam Griffith, James Hargreaves, Katharina Hauck, Tanette Headen, Graeme Hoddinott, Anelet James, Karen Jennings, Sarah Kanema, Barry Kosloff, James Kruger, Ramya Kumar, David Macleod, Nozizwe Makola, Nomtha Mandla, Eric Miller, Ayana Moore, Lawrence Mwenge, Heather Noble, Mwelwa Phiri, Michael Pickles, Kalpana Sabapathy, Ephraim Sakala, Rafael Sauter, Kwame Shanaube, Andrew Silumesi, Nirupama Sista, Tim Skalland, Peter Smith, Ranjeeta Thomas, Sten Vermund, Rhonda White, Ethan Wilson, Blia Yang, Krista Yuhas, Rory Bowden, Vincent Calvez, Max Essex, Kate Grabowski, Ravindra Gupta, Joshua Herbeck, Joseph Kagaayi, Pontiano Kaleebu, Jairam Lingappa, Sikhulile Moyo, Vladimir Novitsky, Thumbi Ndung’u, Deenan Pillay, Thomas Quinn, Andrew Rambaut, Janet Seeley, Deogratius Ssemwanga, Frank Tanser, Maria Wawer |
| Developing best practice public health standards for whole genome sequencing of Mycobacterium tuberculosis | The Lancet Regional Health - Western Pacific | Justin T. Denholm, Marcel A. Behr, Gerard de Vries, Richard Anthony, Esther Robinson, Matthijs Backx, Ian F. Laurenson, Amie-Louise Seagar, Herns Modestil, Lisa Trieu, Jeanne Sullivan Meissner, Deborah Hee Ling Ng, Jun Yang Tay, Hsien-Ho Lin, Robyn Lee, Ellen J. Donnan, Vitali Sintchenko, Ben J. Marais |
| Diagnostic yield as an important metric for the evaluation of novel tuberculosis tests: rationale and guidance for future research | The Lancet Global Health | Tobias Broger, Florian M Marx, Grant Theron, Ben J Marais, Mark P Nicol, Andrew D Kerkhoff, Ruvandhi Nathavitharana, Helena Huerga, Ankur Gupta-Wright, Mikashmi Kohli, Brooke E Nichols, Monde Muyoyeta, Graeme Meintjes, Morten Ruhwald, Rosanna W Peeling, Nitika Pant Pai, Nira R Pollock, Madhukar Pai, Adithya Cattamanchi, David W Dowdy, Puneet Dewan, Claudia M Denkinger |
| Editorial special edition: Addressing antimicrobial resistance in Southeast Asia | One Health | Harish Kumar Tiwari, Justin Beardsley, Ruth Zadoks, Daniel KY Tan, Sothavireak Bory, Phuc Pham Duc, Thi Thu Hoai Nguyen, Watthana Theppangna, |
| Epithelial dendritic cells vs. Langerhans cells: Implications for mucosal vaccines | Cell Reports | Erica Elizabeth Vine, Paul Jonathon Austin, Thomas Ray O’Neil, Najla Nasr, Kirstie Melissa Bertram, Anthony Lawrence Cunningham, Andrew Nicholas Harman |
| Exploring fungal diversity in Vietnam: A citizen science initiative | One Health | Tra-My N. Duong, Minh-Hang Le, Thanh-Van Le, Thuy T. Ha, Maryam Roudbary, Justin Beardsley |
| Farmed fur animals harbour viruses with zoonotic spillover potential | Nature | Zhao, J., Wan, W., Yu, K. Holmes, E et al |
| Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic | Cell | Alexander Crits-Christoph, Joshua I. Levy, Jonathan E. Pekar, Stephen A. Goldstein, Reema Singh, Zach Hensel, Karthik Gangavarapu, Matthew B. Rogers, Niema Moshiri, Robert F. Garry, Edward C. Holmes, Marion P.G. Koopmans, Philippe Lemey, Thomas P. Peacock, Saskia Popescu, Andrew Rambaut, David L. Robertson, Marc A. Suchard, Joel O. Wertheim, Angela L. Rasmussen, Kristian G. Andersen, Michael Worobey, Florence Débarre |
| Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM | The Lancet Infectious Diseases | Christina C Chang, Thomas S Harrison, Tihana A Bicanic, Methee Chayakulkeeree, Tania C Sorrell, Adilia Warris, Ferry Hagen, Andrej Spec, Rita Oladele, Nelesh P Govender, Sharon C Chen, Christopher H Mody, Andreas H Groll, Yee-Chun Chen, Michail S Lionakis, Alexandre Alanio, Elizabeth Castañeda, Jairo Lizarazo, José E Vidal, Takahiro Takazono, Martin Hoenigl, Jan-Willem Alffenaar, Jean-Pierre Gangneux, Rajeev Soman, Li-Ping Zhu, Alexandro Bonifaz, Joseph N Jarvis, Jeremy N Day, Nikolai Klimko, Jon Salmanton-García, Grégory Jouvion, David B Meya, David Lawrence, Sebastian Rahn, Felix Bongomin, Brendan J McMullan, Rosanne Sprute, Tinashe K Nyazika, Justin Beardsley, Fabianne Carlesse, Christopher H Heath, Olusola O Ayanlowo, Olga M Mashedi, Flavio Queiroz-Telles Filho, Mina C Hosseinipour, Atul K Patel, Elvis Temfack, Nina Singh, Oliver A Cornely, David R Boulware, Olivier Lortholary, Peter G Pappas, John R Perfect |
| Host transcriptomics and machine learning for secondary bacterial infections in patients with COVID-19: a prospective, observational cohort study | The Lancet Microbe | Meagan Carney, Tiana Maria Pelaia, Tracy Chew, Sally Teoh, Amy Phu, Karan Kim, Ya Wang, Jonathan Iredell, Yoann Zerbib, Anthony McLean, Klaus Schughart, Benjamin Tang, Maryam Shojaei, Kirsty R Short, Gabriella Cirmena, Alberto Ballestrero, Allan Cripps, Amanda Cox, Andrea De Maria, Arutha Kulasinghe, Carl Feng, Damien Chaussabel, Darawan Rinchai, Davide Bedognetti, Gabriele Zoppoli, Gunawan Gunawan, Irani Thevarajan, Jennifer Audsley, John-Sebastian Eden, Marcela Kralovcova, Marek Nalos, Marko Radic, Martin Matejovic, Michele Bedognetti, Miroslav Prucha, Mohammed Toufiq, Narasaraju Teluguakula, Nicholas West, Paolo Cremonesi, Philip Britton, Ricardo G Branco, Rostyslav Bilyy, Stephen MacDonald, Thomas Karvunidis, Tim Kwan, Velma Herwanto, Win Sen Kuan, Yoann Zerbib, Anthony McLean, Klaus Schughart, Benjamin Tang, Maryam Shojaei, Kirsty R Short |
| Management of the infant born to a mother with tuberculosis: a systematic review and consensus practice guideline | The Lancet Child and Adolescent Health | Nadia Hasan, Clare Nourse, H Simon Schaaf, Adrie Bekker, Marian Loveday, Betina M Alcântara Gabardo, Christopher Coulter, Chishala Chabala, Sushil Kabra, Eilish Moore, Elizabeth Maleche-Obimbo, Nicole Salazar-Austin, Nicole Ritz, Jeffrey R Starke, Andrew P Steenhoff, Rina Triasih, Steven B Welch, Ben J Marais |
| Mapping glycoprotein structure reveals Flaviviridae evolutionary history | Nature | Jonathon C. O. Mifsud, Spyros Lytras, Michael R. Oliver, Kamilla Toon, Vincenzo A. Costa, Edward C. Holmes & Joe Grove |
| Metagenomic analysis of individual mosquito viromes reveals the geographical patterns and drivers of viral diversity | Nature Ecology and Evolution | Pan, YF., Zhao, H., Gou, QY. et al. |
| Mycobacterium tuberculosis produces d-serine under hypoxia to limit CD8+ T cell-dependent immunity in mice | Nature Microbiology | Cheng, H., Ji, Z., Wang, Y. et al. |
| Personalized bacteriophage therapy for difficult-to-treat infections | Nature Microbiology | Jonathan Iredell, Holly Sinclair & Ameneh Khatami |
| Population-wide active case finding as a strategy to end TB | The Lancet Regional Health - Western Pacific | Thu-Anh Nguyen, Alvin Kuo Jing Teo, Yanlin Zhao, Mamel Quelapio, Jeremy Hill, Fukushi Morishita, Ben J. Marais, Guy B. Marks |
| Recombination as an evolutionary driver of MERS-related coronavirus emergence | The Lancet Infectious Diseases | Jarel Elgin Tolentino, Spyros Lytras, Jumpei Ito, Edward C Holmes, Kei Sato |
| Sustained transmission over two decades of a previously unrecognised MPT64 negative Mycobacterium tuberculosis strain in Queensland, Australia: a whole genome sequencing study | The Lancet Regional Health - Western Pacific | Arnold Bainomugisa, Sushil Pandey, Bridget O'Connor, Melanie Syrmis, David Whiley, Vitali Sintchenko, Lachlan J.M. Coin, Ben J. Marais, Christopher Coulter |
| Tackling the threat of antimicrobial resistance in neonates and children: outcomes from the first WHO-convened Paediatric Drug Optimisation exercise for antibiotics | The Lancet Child and Adolescent Health | Alasdair Bamford, Tiziana Masini, Phoebe Williams, Mike Sharland, Valeria Gigante, Devika Dixit, Hatim Sati, Benedikt Huttner, Yasir Bin Nisar, Bernadette Cappello, Wilson Were, Jennifer Cohn, Martina Penazzato |
| The impact of climate change on infant mortality in Viet Nam: identifying a need for higher quality accessible data | The Lancet Regional Health - Western Pacific | Jackson Harrison, Phoebe Williams, Camille Raynes-Greenow, Shane Fairlie, Pham Thi Quynh Nga, Tuan Nghia Ton, Angela Pratt, Ha Ngyuen Thanh, David Payne, Chris McBrearty, Dharmintra Pasupathy |
| The inclusion of children and adolescents in tuberculosis diagnostic development and evaluation–a consensus statement | The Lancet Infectious Diseases | Else M Bijker, Lyn Horn, Sylvia LaCourse, Emily L MacLean, Ben J Marais, Mark P Nicol, Laura Olbrich, James A Seddon, Jayne S Sutherland, Rinn Song, Heather J Zar, Devan Jaganath |
| The patatin-like protein PlpD forms structurally dynamic homodimers in the Pseudomonas aeruginosa outer membrane | Nature Communications | Sarah E. Hanson, Tyrone Dowdy, Mioara Larion, Matthew Thomas Doyle & Harris D. Bernstein |
| Thinking beyond diagnostic accuracy to evaluate tuberculosis screening tests | The Lancet Global Health | Emily L-H MacLean, H Manisha Yapa |
| Virology - The next fifty years | Cell | Edward C. Holmes, Florian Krammer, Felicia D. Goodrum |
| WHO global research priorities for antimicrobial resistance in human health | The Lancet Microbe | Silvia Bertagnolio, Zlatina Dobreva, Chad M Centner et al |
| Widening the lens for pandemic preparedness: children must be seen and heard | The Lancet Regional Health - Western Pacific | Anita J. Campbell, Fiona M. Russell, Ben J. Marais, Philip N. Britton, Asha C. Bowen, Christopher C. Blyth, Katie L. Flanagan, Ameneh Khatami, Archana Koirala, Michelle Mahony, Linny K. Phuong, Nan Vasilunas, Rachel H. Webb, Phoebe C.M. Williams, Brendan J. McMullan |
| Zoonotic tuberculosis in the 21st century | The Lancet Infectious Diseases | Shannon C Duffy, Ben Marais, Vivek Kapur, Marcel A Behr |
| Title | Journal | Authors |
|---|---|---|
| Accelerated SARS-CoV-2 intrahost evolution leading to distinct genotypes during chronic infection | Cell Reports Medicine | Chrispin Chaguza, Anne M. Hahn, Mary E. Petrone, Shuntai Zhou, David Ferguson, Mallery I. Breban, Kien Pham, Mario A. Peña-Hernández, Christopher Castaldi, Verity Hill, Kendall Billig, Rebecca Earnest, Joseph R. Fauver, Chaney C. Kalinch, Nicholas Kerantzas, Tobias R. Koch, Bony De Kumar, Marie L. Landry, Isabel M. Ott, David Peaper, Irina R. Tikhonova, Chantal B.F. Vogels, Wade Schulz, Ronald I. Swanstrom, Scott C. Roberts, Nathan D. Grubaugh |
| Advancing pathogen genomics in resource-limited settings | Cell Genomics | Paul Michael Pronyk, Ruklanthi de Alwis, Rebecca Rockett, Kerri Basile, Yann Felix Boucher, Vincent Pang, October Sessions, Marya Getchell, Tanya Golubchik, Connie Lam, Raymond Lin, Tze-Minn Mak, Ben Marais, Rick Twee-Hee Ong, Hannah Eleanor Clapham, Linfa Wang, Yorin Cahyorini, Francisco Gerardo M. Polotan, Yuni Rukminiati, Eby Sim, Carl Suster, Gavin J.D. Smith, Vitali Sintchenko |
| An evaluation of the landscape structure and La Niña climatic anomalies associated with Japanese encephalitis virus outbreaks reported in Australian piggeries in 2022 | One Health | Michael G. Walsh, Cameron Webb, Victoria Brookes |
| Antimicrobial susceptibility assays for Neisseria gonorrhoeae: a proof-of-principle population-based retrospective analysis | The Lancet Microbe | Sara F E Bell, Robert S Ware, David A Lewis, Monica M Lahra, David M Whiley |
| Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2 | Nature Communications | Kerry L. Hilligan, Sivaranjani Namasivayam, Chad S. Clancy, Paul J. Baker, Samuel I. Old, Victoria Peluf, Eduardo P. Amaral, Sandra D. Oland, Danielle O’Mard, Julie Laux, Melanie Cohen, Nicole L. Garza, Bernard A. P. Lafont, Reed F. Johnson, Carl G. Feng, Dragana Jankovic, Olivier Lamiable, Katrin D. Mayer-Barber & Alan Sher |
| COVID-19 related ICU admissions in paediatric and young adult patients in Australia: a national case series 2020–2022 | The Lancet Regional Health - Western Pacific | Madeleine Otto, Philip N. Britton, Ary Serpa Neto, Simon Erickson, Marino Festa, Nigel W. Crawford, Aidan J.C. Burrell, Andrew A. Udy |
| Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis | The Lancet Child and Adolescent Health | Kenneth S Gunasekera, Olivier Marcy, Johanna Muñoz, Elisa Lopez-Varela, Moorine P Sekadde, Molly F Franke, Maryline Bonnet, Shakil Ahmed, Farhana Amanullah, Aliya Anwar, Orvalho Augusto, Rafaela Baroni Aurilio, Sayera Banu, Iraj Batool, Annemieke Brands, Kevin P Cain, Lucía Carratalá-Castro, Maxine Caws, Eleanor S Click, Lisa M Cranmer, Alberto L García-Basteiro, Anneke C Hesseling, Julie Huynh, Senjuti Kabir, Leonid Lecca, Anna Mandalakas, Farai Mavhunga, Aye Aye Myint, Kyaw Myo, Dorah Nampijja, Mark P Nicol, Patrick Orikiriza, Megan Palmer, Clemax Couto Sant'Anna, Sara Ahmed Siddiqui, Jonathan P Smith, Rinn Song, Nguyen Thuy Thuong Thuong, Vibol Ung, Marieke M van der Zalm, Sabine Verkuijl, Kerri Viney, Elisabetta G Walters, Joshua L Warren, Heather J Zar, Ben J Marais, Stephen M Graham, Thomas P A Debray, Ted Cohen, James A Seddon |
| Effectiveness of COVID-19 vaccination against COVID-19 specific and all-cause mortality in older Australians: a population based study | The Lancet Regional Health - Western Pacific | Bette Liu, Sandrine Stepien, Timothy Dobbins, Heather Gidding, David Henry, Rosemary Korda, Lucas Mills, Sallie-Anne Pearson, Nicole Pratt, Claire M. Vajdic, Jennifer Welsh, Kristine Macartney |
| Exploring programmatic indicators of tuberculosis control that incorporate routine Mycobacterium tuberculosis sequencing in low incidence settings: a comprehensive (2017–2021) patient cohort analysis | The Lancet Regional Health - Western Pacific | Xiaomei Zhang, Elena Martinez, Connie Lam, Taryn Crighton, Eby Sim, Mailie Gall, Ellen J. Donnan, Ben J. Marais, Vitali Sintchenko |
| Host phylogeny shapes viral transmission networks in an island ecosystem | Nature Ecology and Evolution | Rebecca K. French, Sandra H. Anderson, Kristal E. Cain, Terry C. Greene, Maria Minor, Colin M. Miskelly, Jose M. Montoya, Michelle Wille, Chris G. Muller, Michael W. Taylor, Andrew Digby, Kākāpō Recovery Team & Edward C. Holmes |
| Host traits shape virome composition and virus transmission in wild small mammals | Cell | Yan-Mei Chen, Shu-Jian Hu, Xian-Dan Lin, Jun-Hua Tian, Jia-Xin Lv, Miao-Ruo Wang, Xiu-Qi Luo, Yuan-Yuan Pei, Rui-Xue Hu, Zhi-Gang Song, Edward C. Holmes, Yong-Zhen Zhang |
| Human health depends on thriving oceans | The Lancet | Aaron P Jenkins, Alana M S N Lancaster, Anthony Capon, Katy Soapi, Lora E Fleming, Stacy D Jupiter |
| Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential | Nature Communications | Jing Wang, Yuan-fei Pan, Li-fen Yang, Wei-hong Yang, Kexin Lv, Chu-ming Luo, Juan Wang, Guo-peng Kuang, Wei-chen Wu, Qin-yu Gou, Gen-yang Xin, Bo Li, Huan-le Luo, Shoudeng Chen, Yue-long Shu, Deyin Guo, Zi-Hou Gao, Guodong Liang, Jun Li, Yao-qing Chen, Edward C. Holmes, Yun Feng & Mang Shi |
| Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria | Nature Communications | Mu, A., Klare, W.P., Baines, S.L. et al. |
| Invasive aspergillosis in adult patients in Australia and New Zealand: 2017–2020 | The Lancet Regional Health - Western Pacific | Shio Yen Tio, Sharon CA. Chen, Kate Hamilton, Christopher H. Heath, Alyssa Pradhan, Arthur J. Morris, Tony M. Korman, Orla Morrissey, Catriona L. Halliday, Sarah Kidd, Timothy Spelman , Nadiya Brell, Brendan McMullan , Julia E. Clark, Katerina Mitsakos, Robyn P. Hardiman, Phoebe Williams, Anita J. Campbell, Justin Beardsley, Sebastiaan Van Hal , Monica A. Slavin |
| Key lessons from the COVID-19 public health response in Australia | The Lancet Regional Health - Western Pacific | JM Basseal, CM Bennett, P Collignon, BJ Currie, DN Durrheim, J Leask, ES McBryde, P McIntyre, FM Russell, DW Smith, TC Sorrell, BJ Marais |
| Mapping access to drug outlets in Vietnam: distribution of drug outlets and the sociodemographic characteristics of the communities they serve | The Lancet Regional Health - Western Pacific | Justin Beardsley, Joshua Mark Chambers, Thanh Tuan Lam, Shukry Zawahir, Hien Le, Thu Anh Nguyen, Michael Walsh, Pham Thi Thuy Van, Nguyen Thi Cam Van, Tran Huy Hoang, Tran Thi Mai Hung, Cao Hung Thai, Dang Duc Anh, Greg J. Fox |
| On the mechanisms of lysis triggered by perturbations of bacterial cell wall biosynthesis | Nature Communications | Yoshikazu Kawai, Maki Kawai, Eilidh Sohini Mackenzie, Yousef Dashti, Bernhard Kepplinger, Kevin John Waldron & Jeff Errington |
| Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis | Nature Communications | Deborah Cromer, Megan Steain, Arnold Reynaldi, Timothy E. Schlub, Shanchita R. Khan, Sarah C. Sasson, Stephen J. Kent, David S. Khoury & Miles P. Davenport |
| Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers | New England Journal of Medicine | Laure F. Pittet, Nicole L. Messina, Francesca Orsini, M.Sc., Cecilia L. Moore, Ph.D., Veronica Abruzzo, M.Clin.Epi., Simone Barry, Ph.D., Rhian Bonnici, B.Sc., Marc Bonten, Ph.D., John Campbell, M.D., Julio Croda, Margareth Dalcolmo, Ph.D., Kaya Gardiner, M.P.H., Grace Gell, B.Sc., Susie Germano, B.Sc., Adriano Gomes-Silva, Ph.D., Casey Goodall, B.Eng., Amanda Gwee, Ph.D., Tenaya Jamieson, M.Sc., Bruno Jardim, M.Sc., Tobias R. Kollmann, Ph.D., Marcus V.G. Lacerda, Ph.D., Katherine J. Lee, Ph.D., Michaela Lucas, M.D., David J. Lynn, Ph.D., Laurens Manning, Ph.D., Helen S. Marshall, M.D., Ellie McDonald, Ph.D., Craig F. Munns, Ph.D., Suellen Nicholson, B.Sc., Abby O’Connell, Ph.D., Roberto D. de Oliveira, Ph.D., Susan Perlen, Ph.D., Kirsten P. Perrett, Ph.D., Cristina Prat-Aymerich, Ph.D., Peter C. Richmond, M.B., B.S., Jesus Rodriguez-Baño, Ph.D., Glauce dos Santos, M.Sc., Patricia V. da Silva, Ph.D., Jia Wei Teo, B.Sc., Paola Villanueva, B.Med.Sc., Adilia Warris, Ph.D., Nicholas J. Wood, Ph.D., Andrew Davidson, M.D., and Nigel Curtis, Ph.D., for the BRACE Trial Consortium Group |
| Reversing the neglect of children and adolescents affected by tuberculosis | The Lancet Child and Adolescent Health | Stijn Deborggraeve, Martina Casenghi, Catherine Hewison, John Ditekemena, Lucica Ditiu, Farhana Amanullah, Ben J Marais |
| Seroprevalence and prevention of hepatitis B, measles and rubella among healthcare workers in Dili, Timor-Leste | The Lancet Regional Health - Southeast Asia | Celia Gusmao a, Maria Y. Tanesi b, Nelia Gomes b, Sarah L. Sheridan c, Nevio Sarmento b, Tessa Oakley b, Michael David d e, Johanna Wapling b, Lucsendar Alves b, Salvador Amaral b, Anthony D.K. Draper b f, Bernardino Cruz g, Danina Coelho g, Helio Guterres a, Nicholas S.S. Fancourt b, Jennifer Yan b, Kristine Macartney c h, Joshua R. Francis b j, Paul Arkell b i j |
| The case for including microbial sequences in the electronic health record | Nature Medicine | Vitali Sintchenko & Enrico Coiera |
| The evolution and international spread of extensively drug resistant Shigella sonnei | Nature Communications | Lewis C. E. Mason, David R. Greig, Lauren A. Cowley, Sally R. Partridge, Elena Martinez, Grace A. Blackwell, Charlotte E. Chong, P. Malaka De Silva, Rebecca J. Bengtsson, Jenny L. Draper, Andrew N. Ginn, Indy Sandaradura, Eby M. Sim, Jonathan R. Iredell, Vitali Sintchenko, Danielle J. Ingle, Benjamin P. Howden, Sophie Lefèvre, Elisabeth Njamkepo, François-Xavier Weill, Pieter-Jan Ceyssens, Claire Jenkins & Kate S. Baker |
| Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium | The Lancet Digital Health | David Shaw, Raquel Abad, Zahin Amin-Chowdhury et al |
| Tuberculosis in older adults: challenges and best practices in the Western Pacific Region | The Lancet Regional Health - Western Pacific | Alvin Kuo Jing Teo, Fukushi Morishita, Tauhid Islam, Kerri Viney, Catherine W.M. Ong, Seiya Kato, HeeJin Kim, Yuhong Liu, Kyung Hyun Oh, Takashi Yoshiyama, Akihiro Ohkado, Kalpeshsinh Rahevar, Lisa Kawatsu, Manami Yanagawa, Kiesha Prem, Siyan Yi, Huong Thi Giang Tran, Ben J. Marais |
| Understanding SARS-CoV-2 Delta and Omicron variant transmission and vaccine impact in schools and child-care settings in Australia: a population-based study | The Lancet Regional Health - Western Pacific | A. Koirala, N.E. Winkler, H.E. Quinn, E. Gardiner, B. Liu, J. Forbes, C. Sharpe, T. van Tussenbroek, N. Wood, K. Macartney |
| Zoonotic risk assessment among farmed mammals | Cell | Meng Lu, Wan-Ting He, John H.-O. Pettersson, Guy Baele, Mang Shi, Edward C. Holmes, Na He, Shuo Su |
| Title | Publication | Author |
|---|---|---|
| COVID-19: talk of ‘vaccine hesitancy’ lets governments off the hook | Nature | Katie Attwell, Adam Hannah & Julie Leask |
| Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice | Nature Communications | Anneliese S. Ashhurst, Matt D. Johansen, Joshua W. C. Maxwell, Skye Stockdale, Caroline L. Ashley, Anupriya Aggarwal, Rezwan Siddiquee, Stefan Miemczyk, Duc H. Nguyen, Joel P. Mackay, Claudio Counoupas, Scott N. Byrne, Stuart Turville, Megan Steain, James A. Triccas, Philip M. Hansbro, Richard J. Payne & Warwick J. Britton |
| Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine | Nature Communications | Luke J. Dowman, Sameer S. Kulkarni, Juan V. Alegre-Requena, Andrew M. Giltrap, Alexander R. Norman, Ashish Sharma, Liliana C. Gallegos, Angus S. Mackay, Adarshi P. Welegedara, Emma E. Watson, Damian van Raad, Gerhard Niederacher, Susanne Huhmann, Nicholas Proschogo, Karishma Patel, Mark Larance, Christian F. W. Becker, Joel P. Mackay, Girish Lakhwani, Thomas Huber, Robert S. Paton & Richard J. Payne |
| Off-season RSV epidemics in Australia after easing of COVID-19 restrictions | Nature Communications | John-Sebastian Eden, Chisha Sikazwe, Ruopeng Xie, Yi-Mo Deng, Sheena G. Sullivan, Alice Michie, Avram Levy, Elena Cutmore, Christopher C. Blyth, Philip N. Britton, Nigel Crawford, Xiaomin Dong, Dominic E. Dwyer, Kimberly M. Edwards, Bethany A. Horsburgh, David Foley, Karina Kennedy, Cara Minney-Smith, David Speers, Rachel L. Tulloch, Edward C. Holmes, Vijaykrishna Dhanasekaran, David W. Smith, Jen Kok, the Australian RSV study group |
| Co-infection with SARS-CoV-2 Omicron and Delta variants revealed by genomic surveillance | Nature Communications | Rebecca J. Rockett, Jenny Draper, Mailie Gall, Eby M. Sim, Alicia Arnott, Jessica E. Agius, Jessica Johnson-Mackinnon, Winkie Fong, Elena Martinez, Alexander P. Drew, Clement Lee, Christine Ngo, Marc Ramsperger, Andrew N. Ginn, Qinning Wang, Michael Fennell, Danny Ko, Linda Hueston, Lukas Kairaitis, Edward C. Holmes, Matthew N. O’Sullivan, Sharon C.-A. Chen, Jen Kok, Dominic E. Dwyer & Vitali Sintchenko |
| Rough and smooth variants of Mycobacterium abscessus are differentially controlled by host immunity during chronic infection of adult zebrafish | Nature Communications | Julia Y. Kam, Elinor Hortle, Elizabeth Krogman, Sherridan E. Warner, Kathryn Wright, Kaiming Luo, Tina Cheng, Pradeep Manuneedhi Cholan, Kazu Kikuchi, James A. Triccas, Warwick J. Britton, Matt D. Johansen, Laurent Kremer & Stefan H. Oehlers |
| RNA viromes from terrestrial sites across China expand environmentalviral diversity | Nature Microbiology | Yan-Mei Chen, Sabrina Sadiq, Jun-Hua Tian, Xiao Chen, Xian-Dan Lin, Jin-Jin Shen, Hao Chen, Zong-Yu Hao, Michelle Wille, Zhuo-Cheng Zhou, Jun Wu, Feng Li, Hong-Wei Wang, Wei-Di Yang, Qi-Yi Xu, Wen Wang, Wen-Hua Gao, Edward C. Holmes & Yong-Zhen Zhang |
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| Predictors of confidence and trust in government and institutions during the COVID-19 response in Australia | The Lancet Regional Health -Western Pacific | Brooke Nickel, Kristen Pickles, Erin Cvejic, Tessa Copp, Rachael H Dodd, Carissa Bonner, Holly Seale, Maryke Steffens, Gideon Meyerowitz-Katz, Kirsten McCaffery |
| Inappropriate supply of antibiotics for common viral infections by community pharmacies in Vietnam: A standardised patient survey | The Lancet Regional Health -Western Pacific | Shukry Zawahir, Hien Thi Thu Le, Thu-Anh Nguyen, Justin Beardsley, Anh Duc Dang, Sarah Bernays, Kerri Viney, Thai Hung Cao, Dorothy Drabarek, Hoang Huy Tran, Son Tu Nguyen, Van Thi Thuy Pham, Tan Minh Luong, Hung Thi Mai Tran, Nhung Viet Nguyen, Stephen Jan, Ben J Marais, Joel Negin, Guy B Marks, Greg J Fox |
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The image bank is a historic archive of images produced by Dr John Walker during his career as a medical parasitologist.
Dr John Walker is a University of Sydney alumni who worked at the Sydney School of Public Health and Westmead Hospital as a Senior Lecturer in Parasitology for 38 years. His work focused on diagnostic parasitology and epidemiological surveys of gastrointestinal parasites, malaria and filariasis.
A major emphasis of his latter work was providing malaria reference laboratory services and maintenance of a register of malaria cases imported into NSW. Dr Walker retired in 2005 but has retained his interest in parasitology.
Mailing address
Westmead Hospital
Level 5, Block K
Westmead NSW 2145
